Well, it didn't have to be regex:

on *:input:#:{
  if ($istokcs(+o -o,$1,32)) {
    if (!$nick(#,$me,&~)) {
      notice $me I need to be an admin or owner to use this script.
    }
    else {
      mode # $1 $iif(!$2,$me,$2)
    }
  }
}