I don\'t think there would be a way to do that on Caelestia(My Network) as the bot is in the channel, if you want that, try adding this line:

on :text:nick:: {
var %ignorenick <list of nick\'s/bots to ignore>
var %chan $chan
if ($chan == $null) var %Chan PM
set %nick $nick
if ($nick !isin %ignorenick) {
/window -ek0 +ts @highlight -1 -1 700 125 /ReplyHighlight
/aline -h 4 @highlight $timestamp $nick highlighted you on %chan
/aline -h 5 @highlight < $nick > $1-
}
}
alias ReplyHighlight {
/aline -i 14 @highlight My reply: $1-
.notice %nick $1-
}

Replacing <ignore nick/bot> with a list.