This should actually be posted in the forum I think but...
Here's might what you're looking for:
Both searches for a quote with the specified query. The first line with the wilcardmatch of your query will be echoed in your active window or messaged to the channel.
Alias version:

alias searchquote {
  if $1 {
    if $read(Talk.txt,w, * [ $+ [ $1- ] $+ ] *) {
      echo -a Result found:
      echo -a $v1
    }
    else {
      echo -a No result were found.
    }
  }
  else {
    echo -a You need to specify a something to search for.
  }
}

Bot version:

on *:text:!searchquote*:#:{
  if $2 {
    if $read(Talk.txt,w, * [ $+ [ $2- ] $+ ] *) {
      msg $chan Result found:
      msg $chan $v1
    }
    else {
      msg $chan No result were found.
    }
  }
  else {
    msg $chan You need to specify a something to search for.
  }
}

Edit: Changed the $read part in echo/msg to $v1. (facepalm)