Kirby commented on a Page, Anti-advertisement Bot  -  Feb 27, 2009
on $*:TEXT:/(www\56|\57\57\56|\72\57\57|\43[a-zA-Z]|.com|.net|.org)/iS:*: {

You don't want * for # if you're going to have

if ($nick isreg #) {

I'm sure it works...I just tested it.

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