The script worked fine. But the complement code is necessary to not fail.

The relay bot don't need to be an operator to continue the process. But the oppedbot yes.
Then, I completed the code with "if {([botonchan $nospamchan]) && ([onchan $oppedbot $nospamchan]) && (![isbotnick $nick])} { }".

I forgot to edit the pubm...

bind pubm - * pub:spam:check
proc pub:spam:check {nick uhost hand chan text} {
  global spamwords oppedbot
  if {[channel get $chan spamcheck]} {
    foreach pattern $spamwords {
      if {[string match -nocase $pattern $text]} {
    if {([botonchan $nospamchan]) && ([onchan $oppedbot $nospamchan]) && (![isbotnick $nick])} {
          if {(![validuser $hand]) && (![isop $nick $chan]) && (![isvoice $nick $chan])} {
            putquick "PRIVMSG $oppedbot :spam $chan $nick"
      }
        }
      }
    }
  }
  return 0
}

fixed 1:

bind msgm - * msg:spam:check
proc msg:spam:check {nick uhost hand text} { 
  global spamwords oppedbot
  foreach nospamchan [channels] {
    if {[channel get $nospamchan spamcheck]} {
      if {([botonchan $nospamchan]) && ([onchan $oppedbot $nospamchan]) && (![isbotnick $nick])} { 
        if {([onchan $nick $nospamchan]) && (![validuser $hand]) && (![isop $nick $nospamchan]) && (![isvoice $nick $nospamchan])} {
          foreach pattern $spamwords {
            if {[string match -nocase $pattern $text]} {
              putquick "PRIVMSG $oppedbot :spam $nospamchan $nick" 
            }
          }
        }
      }
    } 
  } 
  return 0
}

fixed 2:

bind CTCP - ACTION spam:check
proc spam:check {nick uhost hand dest key text} {
  global botnick spamwords oppedbot
  foreach nospamchan [channels] {
    if {[channel get $nospamchan spamcheck]} {
      if {([botonchan $nospamchan]) && ([onchan $oppedbot $nospamchan]) && (![isbotnick $nick])} {
        if {![validuser $hand]} {
          if {([onchan $nick $nospamchan]) && (![isop $nick $nospamchan]) && (![isvoice $nick $nospamchan])} {
            foreach pattern $spamwords {
              if {[string match -nocase $pattern $text]} { 
                putquick "PRIVMSG $oppedbot :spam $nospamchan $nick"
              }
            }
          }
        }
      } 
    } 
  }
  return 0
}